Description

2-Chloro-(Trifluoromethyl)Aniline is a versatile halogenated aniline derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both chloro and trifluoromethyl substituents, provides valuable electronic and steric properties for constructing complex molecules. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system and metabolic disorders.
• Agrochemical Synthesis: Building block for novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the trifluoromethyl group.
• Material Science: Used in the development of specialty polymers, liquid crystals, and advanced organic electronic materials.
• Dye and Pigment Manufacturing: Intermediate for producing high-performance, light-fast dyes and pigments.
• Cross-Coupling Reactions: Valuable substrate in palladium-catalyzed reactions like Suzuki and Buchwald-Hartwig amination for C-N bond formation.
• Research & Development: Serves as a standard reagent in academic and industrial R&D for exploring new synthetic methodologies.

Basic Information

Product Name	2-Chloro-(Trifluoromethyl)Aniline
CAS No.	1003709-27-0
Molecular Formula	C7H5ClF3N
Molecular Weight	195.57 g/mol
Synonyms	2-Chloro-α,α,α-trifluoro-p-toluidine; 2-Chloro-4-(trifluoromethyl)aniline; 2-Chloro-4-trifluoromethylaniline; 4-Amino-3-chlorobenzotrifluoride; 3-Chloro-4-aminobenzotrifluoride; Benzenamine, 2-chloro-4-(trifluoromethyl)-; 2-Chloro-α,α,α-trifluoro-p-toluidine
EINECS	Contact for details

Quality Control

Our 2-Chloro-(Trifluoromethyl)Aniline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC, GC, NMR, and IR spectroscopy to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	40 - 45 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.