Description

Quinazoline, 6-Bromo-4-Chloro-2-(Methylthio)- is a high-value, multi-substituted heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a versatile and critical intermediate for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential kinase inhibitors, anticancer agents, and other biologically active quinazoline derivatives.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and pesticides, leveraging the bioactive quinazoline core.
• Material Science: Acts as a building block for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic light-emitting diodes (OLEDs).
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for studying enzyme function and cellular pathways.
• Custom Synthesis & Contract Manufacturing: A crucial starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.
• Academic & Institutional Research: Used in universities and research institutes for methodological development and exploration of new chemical reactions.

Basic Information

Product Name	Quinazoline, 6-Bromo-4-Chloro-2-(Methylthio)-
CAS No.	1003043-76-2
Molecular Formula	C9H6BrClN2S
Molecular Weight	289.58 g/mol
Synonyms	6-Bromo-4-chloro-2-(methylthio)quinazoline; 2-(Methylthio)-6-bromo-4-chloroquinazoline; 4-Chloro-6-bromo-2-methylsulfanylquinazoline; 6-Bromo-4-chloro-2-methylmercaptoquinazoline; Quinazoline, 4-chloro-6-bromo-2-(methylthio)-; 1003043-76-2; 6-Bromo-4-chloro-2-(methylsulfanyl)quinazoline
EINECS	Contact for details

Quality Control

Our Quinazoline, 6-Bromo-4-Chloro-2-(Methylthio)- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production can be aligned with research-grade to cGMP standards based on customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.