Description

2-Ethoxypyrimidine-5-Boronicacid is a specialized organoboron compound, specifically a pyrimidine-substituted boronic acid derivative. This chemical is a crucial building block (synthetic intermediate) in modern organic synthesis, valued for its role in cross-coupling reactions. It is primarily utilized by pharmaceutical R&D and agrochemical scientists for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used to create advanced pyrimidine-based active ingredients for crop protection products.
• Material Science Research: Serves as a monomer or functionalization agent in the development of organic electronic materials and metal-organic frameworks (MOFs).
• Chemical Biology: Employed in the synthesis of probes and ligands for studying biological targets and pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and advanced intermediates.

Basic Information

Product Name	2-Ethoxypyrimidine-5-Boronicacid
CAS No.	1003043-55-7
Molecular Formula	C6H9BN2O3
Molecular Weight	167.96 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-ethoxypyrimidine; 2-Ethoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine; 2-Ethoxypyrimidine-5-boronic acid pinacol ester; (2-Ethoxypyrimidin-5-yl)boronic acid; 1003043-55-7
EINECS	Contact for details

Quality Control

Our 2-Ethoxypyrimidine-5-Boronicacid is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to handle the material under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to minimize exposure to moisture. Recommended storage temperature: 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.