Description

Tau Peptide (306-317) CAS NO 1003007-59-7 is a synthetic peptide fragment corresponding to amino acid residues 306-317 of the human tau protein. This sequence is of significant interest in neurological research, particularly for studying tauopathies such as Alzheimer's disease. It serves as a critical tool for antibody development, epitope mapping, and investigating protein aggregation mechanisms. Researchers in pharmaceutical R&D, biotechnology, and academic neuroscience laboratories require this high-purity peptide for their investigative work.

Application

• Antibody Production & Characterization: Used as an immunogen or antigen for generating and screening monoclonal and polyclonal antibodies specific to the tau protein.
• Biomarker Research: Employed in assay development for detecting tau-related biomarkers in cerebrospinal fluid (CSF) or blood samples.
• Neurodegenerative Disease Studies: A key reagent for in vitro and in vivo research on tau aggregation, phosphorylation, and its role in diseases like Alzheimer's, frontotemporal dementia, and chronic traumatic encephalopathy (CTE).
• Diagnostic Kit Development: Integrated into ELISA, Western Blot, and other immunoassay platforms for diagnostic research and development.
• Epitope Mapping: Essential for defining the specific binding sites (epitopes) of antibodies on the tau protein.
• Protein-Protein Interaction Studies: Used to study the interaction between tau and other proteins or molecules involved in neuronal function and pathology.
• Quality Control Reference Standard: Serves as a reference standard for the quality control of other tau-related reagents and assays.
• Drug Discovery & Screening: Utilized in high-throughput screening (HTS) campaigns to identify potential therapeutic compounds that modulate tau biology.

Basic Information

Product Name	Tau Peptide (306-317)
CAS No.	1003007-59-7
Molecular Formula	C58H95N19O18
Molecular Weight	1306.5 g/mol
Synonyms	Tau (306-317) Peptide; Tau Protein Fragment (306-317); hTau (306-317); VQIINK peptide; VQIINKKLDLS; Alzheimer's Disease Tau Peptide; Microtubule-Associated Protein Tau (306-317); Paired Helical Filament (PHF) Tau Peptide
EINECS	Contact for details

Quality Control

Our Tau Peptide (306-317) is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and MS for identity confirmation, to ensure it meets the high standards required for research. Certificates of Analysis (COA) detailing purity, amino acid analysis, and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term storage, keep desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Amino Acid Composition	Conforms to theoretical values
Net Peptide Content	≥ 70%
Solubility	Soluble in water or dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.