Description

1-(5-Fluoro-Pyrimidin-2-Yl)-Piperidin-4-Ol is a high-purity fluorinated piperidine-pyrimidine hybrid compound, serving as a critical advanced pharmaceutical intermediate. Its value lies in its unique molecular scaffold, which is essential for modulating biological activity in drug discovery and development. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for therapeutic areas requiring targeted molecular structures.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new chemical entities (NCEs) and potential drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore and optimize biological activity profiles.
• API Development: Serves as a precursor in the multi-step synthesis of complex target molecules for preclinical and clinical development.
• Biochemical Tool Compound: May be utilized in biochemical assays to study enzyme inhibition or receptor binding mechanisms.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	1-(5-Fluoro-Pyrimidin-2-Yl)-Piperidin-4-Ol
CAS No.	1001397-31-4
Molecular Formula	C9H12FN3O
Molecular Weight	197.21 g/mol
Synonyms	4-Piperidinol, 1-(5-fluoro-2-pyrimidinyl)-; 1-(5-Fluoropyrimidin-2-yl)piperidin-4-ol; 4-Hydroxy-1-(5-fluoropyrimidin-2-yl)piperidine; 1-(5-Fluoro-2-pyrimidinyl)-4-piperidinol; 1001397-31-4
EINECS	Contact for details

Quality Control

Our 1-(5-Fluoro-Pyrimidin-2-Yl)-Piperidin-4-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.