Description

5-Allyl-6-Chloro-n-(2-Fluoro-4-(Methylsulfonyl)Phenyl)Pyrimidin-4-Amine is a high-purity, synthetically derived pyrimidine derivative, serving as a critical advanced intermediate in modern pharmaceutical research and development. Its complex molecular architecture, featuring distinct functional groups, makes it a valuable building block for constructing novel active pharmaceutical ingredients (APIs). This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical sectors. It enables the synthesis of targeted molecules for therapeutic and crop protection applications.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel small-molecule drug candidates, particularly in oncology and antiviral research.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its pyrimidine core.
• Chemical Biology Probe: Serves as a scaffold for creating molecular probes to study enzyme function and biological pathways.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial-scale production of complex target molecules.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.
• Academic Research: Utilized in university and institutional labs for methodological studies in heterocyclic and medicinal chemistry.

Basic Information

Product Name	5-Allyl-6-Chloro-n-(2-Fluoro-4-(Methylsulfonyl)Phenyl)Pyrimidin-4-Amine
CAS No.	1001397-14-3
Molecular Formula	C14H13ClFN3O2S
Molecular Weight	341.78 g/mol
Synonyms	5-Allyl-6-chloro-N-[2-fluoro-4-(methylsulfonyl)phenyl]pyrimidin-4-amine; 4-Amino-5-allyl-6-chloro-N-(2-fluoro-4-(methylsulfonyl)phenyl)pyrimidine; 1001397-14-3; 5-Allyl-6-chloro-N-(2-fluoro-4-methanesulfonylphenyl)pyrimidin-4-amine; 5-Allyl-6-chloro-N-(2-fluoro-4-methylsulfonylphenyl)-4-pyrimidinamine
EINECS	Contact for details

Quality Control

Our 5-Allyl-6-Chloro-n-(2-Fluoro-4-(Methylsulfonyl)Phenyl)Pyrimidin-4-Amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.