Description

(R)-tert-Butyl 4-(5-Methyl-6,7-Dihydro-5H-Cyclopenta[D]Pyrimidin-4-Yl)Piperazine-1-Carboxylate is a high-purity chiral intermediate of significant importance in modern pharmaceutical research and development. Its value lies in its role as a key building block for synthesizing complex, biologically active molecules, particularly in the creation of novel therapeutics. This compound is essential for R&D chemists and process development scientists in the pharmaceutical and biotechnology industries, where it is used to develop new drug candidates targeting a range of diseases.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Drug Discovery & Medicinal Chemistry: Used in lead optimization and structure-activity relationship (SAR) studies to develop novel drug candidates with improved efficacy and selectivity.
• Process Chemistry & Scale-Up: Employed in the development and optimization of scalable synthetic routes for potential new drugs during clinical trial material production.
• Asymmetric Synthesis: Utilized as a reagent or intermediate in stereoselective synthesis to create enantiomerically pure compounds, which are crucial for many biological applications.
• Biochemical Research: Acts as a tool compound or precursor in biochemical assays to study enzyme mechanisms and cellular pathways.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations that support pharmaceutical companies with custom synthesis and development services.

Basic Information

Product Name	(R)-tert-Butyl 4-(5-Methyl-6,7-Dihydro-5H-Cyclopenta[D]Pyrimidin-4-Yl)Piperazine-1-Carboxylate
CAS No.	1001178-90-0
Molecular Formula	C17H26N4O2
Molecular Weight	318.42 g/mol
Synonyms	(R)-tert-Butyl 4-(5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)piperazine-1-carboxylate; 1-Boc-4-(5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)-(R)-piperazine; (R)-1-(tert-Butoxycarbonyl)-4-(5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)piperazine; (R)-Boc-Piperazine-Cyclopentapyrimidine Derivative; (R)-Boc-Protected Cyclopentapyrimidinylpiperazine; 1001178-90-0; tert-Butyl (R)-4-(5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)piperazine-1-carboxylate
EINECS	Contact for details

Quality Control

Our (R)-tert-Butyl 4-(5-Methyl-6,7-Dihydro-5H-Cyclopenta[D]Pyrimidin-4-Yl)Piperazine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity (assay), chiral purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥97.0%
Chiral Purity (Chiral HPLC)	≥98.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.