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Propargyl 2-Acetamido-2-Deoxy-α-D-Glucoside Solution CAS NO 1000593-95-2
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CAS No.:1000593-95-2
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Propargyl 2-Acetamido-2-Deoxy-α-D-Glucoside Solution is a specialized chemical derivative of N-acetylglucosamine, featuring a propargyl ether group. This functionalization makes it a valuable click chemistry reagent, enabling efficient, modular, and bioorthogonal conjugation strategies in advanced research and development. It is primarily utilized by scientists and manufacturers in the pharmaceutical, biotechnology, and life science sectors for applications such as glycoconjugate synthesis, probe development, and metabolic labeling. The solution format ensures ease of handling and precise volumetric dispensing for laboratory and process-scale work.
Application
- Click Chemistry Reagent: Acts as a key building block for copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC) reactions to label or functionalize biomolecules.
- Glycoconjugate Synthesis: Used in the chemoenzymatic or chemical synthesis of complex oligosaccharides, glycopeptides, and glycoproteins for structural and functional studies.
- Metabolic Labeling Probes: Serves as a precursor for developing probes to study glycan biosynthesis and trafficking in living cells.
- Bioconjugation & Immobilization: Facilitates the site-specific attachment of sugars to surfaces, polymers, proteins, or nanoparticles for biosensing and diagnostic applications.
- Pharmaceutical Intermediate: Employed in the research and development of novel therapeutic agents, including carbohydrate-based vaccines and drug delivery systems.
- Chemical Biology Tool: Enables the exploration of carbohydrate-protein interactions and glycosylation pathways in disease models.
Basic Information
| Item | Details |
|---|---|
| Product Name | Propargyl 2-Acetamido-2-Deoxy-α-D-Glucoside Solution |
| CAS No. | 1000593-95-2 |
| Molecular Formula | C11H17NO6 |
| Molecular Weight | 259.26 g/mol |
| Synonyms | Propargyl N-Acetyl-α-D-glucosaminide; 2-Acetamido-2-deoxy-α-D-glucopyranoside Propargyl Ether; 1-O-Propargyl-2-acetamido-2-deoxy-α-D-glucopyranose; N-Acetyl-α-D-glucosamine Propargyl Glycoside; α-Propargyl GlcNAc; Click Chemistry GlcNAc Reagent; Propargyl-α-GlcNAc |
| EINECS | Contact for details |
Quality Control
Our Propargyl 2-Acetamido-2-Deoxy-α-D-Glucoside Solution is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and process applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory documentation needs.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (typically 15-25°C). The solution is sensitive to strong acids and organic solvents; ensure compatibility with container materials and store separately from incompatible substances. For long-term stability, consider storage under an inert atmosphere if specified.
Specification
| Item | Specification |
|---|---|
| Appearance | Clear, colorless to pale yellow solution |
| Identification (IR / NMR) | Conforms to structure |
| Assay (HPLC) | ≥ 95% (or as per customer requirement) |
| Purity (HPLC) | ≥ 98% |
| Solvent | Specified (e.g., Anhydrous DMF, DMSO, or other) |
| Concentration | Specified (e.g., 0.1M, 0.5M, or custom) |
| Water Content (KF) | < 0.5% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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