Description

Methyl 4-Oxo-3,4-Dihydroquinazoline-8-Carboxylate is a high-purity, advanced pharmaceutical intermediate with a defined molecular structure, essential for modern synthetic chemistry. This compound serves as a critical building block in the development of novel active pharmaceutical ingredients (APIs), particularly for therapeutic agents targeting specific biological pathways. It is primarily required by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development for oncology, neurology, and other specialized therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Drug Discovery Research: Used in medicinal chemistry for the design, synthesis, and structure-activity relationship (SAR) studies of new chemical entities.
• Chemical Biology Probe Synthesis: Employed in the creation of molecular probes for studying enzyme function and biological mechanisms.
• Process Chemistry & Scale-Up: Serves as a starting material or intermediate in the optimization and pilot-scale production of potential therapeutics.
• Reference Standard: Utilized as an analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	Methyl 4-Oxo-3,4-Dihydroquinazoline-8-Carboxylate
CAS No.	1000578-10-8
Molecular Formula	C10H8N2O3
Molecular Weight	204.18 g/mol
Synonyms	8-Quinazolinecarboxylic acid, 3,4-dihydro-4-oxo-, methyl ester; Methyl 4-oxo-3,4-dihydroquinazoline-8-carboxylate; 4-Oxo-3,4-dihydroquinazoline-8-carboxylic acid methyl ester; Methyl 4-oxoquinazoline-8-carboxylate; 8-Methoxycarbonyl-4(3H)-quinazolinone; 4(3H)-Quinazolinone, 8-(methoxycarbonyl)-; 1000578-10-8
EINECS	Contact for details

Quality Control

Our Methyl 4-Oxo-3,4-Dihydroquinazoline-8-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.