Description

3,5-Difluoro-4-Iodophenol is a halogenated phenol derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and critical building block for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought after by R&D chemists and process development scientists for creating active pharmaceutical ingredients (APIs) and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides due to its halogenated aromatic structure.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of monomers for specialty polymers and advanced organic electronic materials.
• Fluorinated Compound Library: A valuable scaffold for medicinal chemistry in building diverse fluorinated compound libraries for high-throughput screening.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific halogenated phenols.

Basic Information

Product Name	3,5-Difluoro-4-Iodophenol
CAS No.	1000574-74-2
Molecular Formula	C6H3F2IO
Molecular Weight	271.99 g/mol
Synonyms	4-Iodo-3,5-difluorophenol; 3,5-Difluoro-4-iodo-1-hydroxybenzene; Phenol, 3,5-difluoro-4-iodo-; 1-Hydroxy-4-iodo-3,5-difluorobenzene
EINECS	Contact for details

Quality Control

Our 3,5-Difluoro-4-Iodophenol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.