Description

4-Bromo-2-Chloro-5-Fluoroaniline is a halogenated aniline derivative that serves as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system and metabolic disorders.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, leveraging its halogenated structure for bioactivity.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers and liquid crystals.
• Dye and Pigment Manufacturing: Intermediate for producing complex, light-fast azo dyes and high-performance pigments.
• Organic Light-Emitting Diodes (OLEDs): Building block for electron-transport materials and emissive layer components in display technologies.
• Chemical Research & Development: Versatile scaffold for medicinal chemistry, facilitating structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	4-Bromo-2-Chloro-5-Fluoroaniline
CAS No.	1000572-63-3
Molecular Formula	C6H4BrClFN
Molecular Weight	224.46 g/mol
Synonyms	2-Chloro-4-bromo-5-fluoroaniline; 5-Fluoro-2-chloro-4-bromoaniline; 4-Bromo-2-chloro-5-fluoro-benzenamine; Benzenamine, 4-bromo-2-chloro-5-fluoro-; 2-Chloro-4-bromo-5-fluoro-phenylamine; 4-Br-2-Cl-5-F-aniline
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Chloro-5-Fluoroaniline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	82 - 86 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.