Description

6-tert-Butyl-2-Hydroxy-Pyrimidine-4-Carboxylic Acid is a high-purity, functionalized pyrimidine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to introduce specific steric and electronic properties into target molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides where the tert-butyl and carboxylic acid functionalities are essential for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating complex chelating ligands used in homogeneous catalysis and material science.
• Fine Chemical Production: Intermediate for manufacturing specialty chemicals, dyes, and advanced polymers requiring specific pyrimidine cores.
• Academic and Industrial R&D: A valuable reagent for methodological development and exploring new chemical spaces in heterocyclic chemistry.

Basic Information

Product Name	6-tert-Butyl-2-Hydroxy-Pyrimidine-4-Carboxylic Acid
CAS No.	1000353-37-6
Molecular Formula	C9H12N2O3
Molecular Weight	196.20 g/mol
Synonyms	2-Hydroxy-6-tert-butylpyrimidine-4-carboxylic acid; 6-(tert-Butyl)-2-hydroxypyrimidine-4-carboxylic acid; 4-Pyrimidinecarboxylic acid, 6-(1,1-dimethylethyl)-2-hydroxy-; 6-tert-Butyl-2-hydroxypyrimidine-4-carboxylic acid; 6-tert-Butyl-2-oxo-1,2-dihydropyrimidine-4-carboxylic acid; 6-(tert-Butyl)-2-oxo-1,2-dihydropyrimidine-4-carboxylic acid; TBPCA (abbreviation)
EINECS	Contact for details

Quality Control

Our 6-tert-Butyl-2-Hydroxy-Pyrimidine-4-Carboxylic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.