Description

4,7-Difluoro (1H)Indazole is a high-purity fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where the introduction of fluorine atoms can dramatically alter biological activity and metabolic stability. It is primarily sought after by research institutions and industrial-scale manufacturers in the pharmaceutical, agrochemical, and material science sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and pesticides with enhanced efficacy and environmental profiles.
• Material Science: Serves as a building block for advanced organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge transport materials.
• Chemical Biology: Employed as a probe or tag in medicinal chemistry and biochemical research due to its fluorinated structure.
• Custom Synthesis: Utilized by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects requiring fluorinated indazole cores.
• Ligand Development: Acts as a scaffold for creating novel ligands in catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	4,7-Difluoro (1H)Indazole
CAS No.	1000341-68-3
Molecular Formula	C7H4F2N2
Molecular Weight	154.12 g/mol
Synonyms	1H-Indazole, 4,7-difluoro-; 4,7-Difluoro-1H-indazole; 4,7-Difluoroindazole; 4,7-Difluoro-1H-indazole; 1000341-68-3; 4,7-Difluoroindazole (1H-Indazole, 4,7-difluoro-); 4,7-Difluoro-1H-indazole (9CI)
EINECS	Contact for details

Quality Control

Our 4,7-Difluoro (1H)Indazole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.