Description

2-(2-Aminopyrimidin-4-Yl)-5-Morpholinophenol is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring both aminopyrimidine and morpholinophenol moieties, makes it a critical intermediate for constructing complex pharmacologically active molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of kinase inhibitors and other targeted therapeutic agents. Its precise structure enables the exploration of novel chemical space in drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of small-molecule kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of novel active ingredients for crop protection.
• Chemical Biology: Serves as a versatile scaffold for designing molecular probes and tool compounds.
• Organic Synthesis Building Block: Employed in complex multi-step syntheses requiring specific heterocyclic coupling.
• Material Science Research: Investigated as a component in the design of organic electronic materials and ligands for catalysis.

Basic Information

Product Name	2-(2-Aminopyrimidin-4-Yl)-5-Morpholinophenol
CAS No.	1000340-04-4
Molecular Formula	C14H15N5O2
Molecular Weight	285.30 g/mol
Synonyms	5-Morpholino-2-(2-pyrimidinylamino)phenol; 2-(2-Aminopyrimidin-4-yl)-5-morpholin-4-ylphenol; 4-(4-Hydroxy-3-(2-aminopyrimidin-4-yl)phenyl)morpholine; Phenol, 5-morpholino-2-(2-pyrimidinylamino)-; 1000340-04-4
EINECS	Contact for details

Quality Control

Our 2-(2-Aminopyrimidin-4-Yl)-5-Morpholinophenol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP starting material requirements. Specifications are designed to meet the high standards of pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C or as specified on the label. This material is hygroscopic (moisture-sensitive) and easily oxidized; therefore, containers must be kept tightly sealed and allowed to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.