Description

3-Nitro-4-(2,2,2-trifluoroethoxy)aniline is a specialized aromatic amine derivative featuring a nitro group and a trifluoroethoxy substituent, which imparts unique electronic and steric properties. This compound serves as a critical advanced pharmaceutical intermediate (API intermediate) and a versatile building block in the synthesis of complex organic molecules. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and pesticides, leveraging its unique fluorine-containing structure.
• Dye and Pigment Manufacturing: Acts as an intermediate for producing specialized azo dyes and high-performance pigments.
• Liquid Crystal & OLED Materials: Serves as a building block for electronic chemicals used in display technologies.
• Polymer Modification: Employed to introduce functional amine and fluorinated groups into polymer chains for enhanced material properties.
• Organic Synthesis & Catalysis Research: A valuable reagent for academic and industrial research in developing new synthetic methodologies and catalytic processes.

Basic Information

Item	Details
Product Name	3-Nitro-4-(2,2,2-trifluoroethoxy)aniline
CAS No.	1000339-84-3
Molecular Formula	C8H7F3N2O3
Molecular Weight	236.15 g/mol
Synonyms	1-Amino-2-nitro-4-(2,2,2-trifluoroethoxy)benzene; 4-Amino-2-nitro-1-(2,2,2-trifluoroethoxy)benzene; 2-Nitro-4-(2,2,2-trifluoroethoxy)aniline; 3-Nitro-4-(2,2,2-trifluoroethoxy)benzenamine; Benzenamine, 3-nitro-4-(2,2,2-trifluoroethoxy)-; 4-(2,2,2-Trifluoroethoxy)-3-nitroaniline
EINECS	Contact for details

Quality Control

Our production of 3-Nitro-4-(2,2,2-trifluoroethoxy)aniline adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. We provide detailed Certificates of Analysis (COA) for all shipments, documenting identity, purity, and impurity profiles. Our quality systems are designed to support cGMP compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.