Description

2-Methoxy-3-(Trifluoromethyl)Benzaldehyde is a versatile fluorinated aromatic aldehyde building block. This compound is valued for its unique trifluoromethyl and methoxy substituents, which impart specific electronic and steric properties critical for advanced synthesis. It is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients. Its structure makes it a key intermediate in creating molecules with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and central nervous system (CNS) targeted drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances lipophilicity and biological activity.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and advanced polymers with tailored electronic properties.
• Fluorine Chemistry Studies: An important building block for exploring structure-activity relationships (SAR) in medicinal and agrochemical discovery programs.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production under cGMP conditions.

Basic Information

Product Name	2-Methoxy-3-(Trifluoromethyl)Benzaldehyde
CAS No.	1000339-54-7
Molecular Formula	C9H7F3O2
Molecular Weight	204.15 g/mol
Synonyms	3-(Trifluoromethyl)-2-methoxybenzaldehyde; 2-Methoxy-α,α,α-trifluoro-m-tolualdehyde; m-Tolualdehyde, 2-methoxy-α,α,α-trifluoro-; 2-Methoxy-3-trifluoromethylbenzaldehyde; Benzaldehyde, 2-methoxy-3-(trifluoromethyl)-; 3-Trifluoromethyl-2-methoxybenzaldehyde
EINECS	Contact for details

Quality Control

Our 2-Methoxy-3-(Trifluoromethyl)Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.