Description

3-Fluoro-4-[(1-Methylpiperidin-4-Yl)Methoxy]Aniline is a high-purity, advanced pharmaceutical intermediate featuring a unique aniline derivative structure with a fluorinated aromatic ring and a piperidine moiety. This compound is critical for medicinal chemistry research and development, serving as a key building block in the synthesis of targeted small molecule therapeutics. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel drug candidates, particularly in oncology and central nervous system (CNS) applications.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel active pharmaceutical ingredients (APIs) targeting specific biological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Kinase Inhibitor Development: Serves as a core scaffold in the design and synthesis of potential kinase inhibitors for oncology treatments.
• CNS Drug Candidates: Employed in the research of compounds targeting neurological disorders, leveraging the piperidine moiety for blood-brain barrier permeability.
• Chemical Biology Probes: Utilized to create labeled or tagged molecules for studying protein-ligand interactions and cellular processes.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for client projects.

Basic Information

Product Name	3-Fluoro-4-[(1-Methylpiperidin-4-Yl)Methoxy]Aniline
CAS No.	1000053-56-4
Molecular Formula	C13H19FN2O
Molecular Weight	238.30 g/mol
Synonyms	4-[(1-Methyl-4-piperidinyl)methoxy]-3-fluoroaniline; 3-Fluoro-4-((1-methylpiperidin-4-yl)methoxy)benzenamine; 3-Fluoro-4-[(1-methyl-4-piperidinyl)methoxy]aniline; 3-Fluoro-4-[(1-methylpiperidin-4-yl)methoxy]phenylamine; Benzenamine, 3-fluoro-4-[(1-methyl-4-piperidinyl)methoxy]-; 3-Fluoro-4-(1-methylpiperidin-4-ylmethoxy)aniline
EINECS	Contact for details

Quality Control

Our 3-Fluoro-4-[(1-Methylpiperidin-4-Yl)Methoxy]Aniline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with client specifications and supporting regulatory filings for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.