Description

L-Buthionine Sulfoxide is a key biochemical reagent and a stable sulfoxide derivative of the glutathione synthesis inhibitor, L-buthionine sulfoximine. This compound is essential for research into cellular redox balance, oxidative stress, and glutathione metabolism. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors for drug discovery, metabolic studies, and as a critical reference standard.

Application

• Biochemical Research: A vital tool for studying glutathione biosynthesis inhibition and its effects on cellular oxidative stress pathways.
• Pharmaceutical Development: Used as a reference standard and intermediate in the research and development of drugs targeting cancer, neurodegenerative diseases, and conditions related to oxidative damage.
• Metabolic Studies: Employed in in vitro and in vivo models to investigate the role of glutathione in detoxification, immune function, and cellular protection.
• Academic Research: A critical reagent for universities and research institutions conducting fundamental studies in biochemistry, molecular biology, and pharmacology.
• Diagnostic Reagent Manufacturing: Potential use as a component or calibrant in diagnostic kits and assays measuring oxidative stress markers.

Basic Information

Product Name	L-Buthionine Sulfoxide
CAS No.	199982-01-9
Molecular Formula	C8H17NO3S
Molecular Weight	207.29 g/mol
Synonyms	L-BSO; (2S)-2-Amino-4-(butylsulfinyl)butanoic acid; L-Buthionine (R)-S-oxide; Buthionine Sulfoxide; L-Buthionine S-Oxide; (S)-2-Amino-4-(butylsulfinyl)butyric acid; NSC 326231; BSO
EINECS	Contact for details

Quality Control

Our L-Buthionine Sulfoxide is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via spectroscopic methods. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	[α]²⁰D: Specific range provided on COA
Chiral Purity	≥ 99.0% (by chiral HPLC)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.