Description

2-Amino-4-Chloro-6-Cyclobutylpyrimidine is a high-purity, functionalized pyrimidine derivative serving as a critical building block in advanced organic synthesis. Its unique structure, featuring a cyclobutyl substituent, makes it a valuable intermediate for constructing complex molecules with specific steric and electronic properties. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in kinase inhibitor and antiviral agent programs.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, where the pyrimidine core is a common bioactive motif.
• Material Science Research: Serves as a precursor for the synthesis of specialized ligands and organic electronic materials.
• Chemical Biology: Employed in the design and synthesis of molecular probes and enzyme inhibitors for biochemical studies.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and fine chemical manufacturers performing bespoke synthesis.

Basic Information

Product Name	2-Amino-4-Chloro-6-Cyclobutylpyrimidine
CAS No.	199863-85-9
Molecular Formula	C8H10ClN3
Molecular Weight	183.64 g/mol
Synonyms	4-Chloro-6-cyclobutylpyrimidin-2-amine; 6-Cyclobutyl-4-chloropyrimidin-2-amine; 2-Pyrimidinamine, 4-chloro-6-cyclobutyl-; 4-Chloro-6-cyclobutyl-2-pyrimidinamine; 2-Amino-4-chloro-6-cyclobutyl-pyrimidine; 4-Chloro-6-cyclobutyl-2-aminopyrimidine; 6-Cyclobutyl-4-chloro-2-pyrimidinamine
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-4-Chloro-6-Cyclobutylpyrimidine is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes results from HPLC, NMR, and other relevant spectroscopic methods. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.