Description

4-Chloro-5,6-Dimethyl-2-(4-Fluorophenylamino)Pyrimidine is a high-purity, advanced pharmaceutical intermediate with a defined heterocyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the research and synthesis of novel drug candidates, especially kinase inhibitors and other targeted therapies.
• Agrochemical Research: Serves as a precursor in the development of new herbicides and fungicides with specific modes of action.
• Chemical Synthesis: Used in organic synthesis for constructing complex pyrimidine-based heterocycles in academic and industrial R&D settings.
• Material Science: Potential intermediate for the development of specialty polymers and advanced organic electronic materials.

Basic Information

Product Name	4-Chloro-5,6-Dimethyl-2-(4-Fluorophenylamino)Pyrimidine
CAS No.	199463-20-2
Molecular Formula	C12H11ClFN3
Molecular Weight	251.69 g/mol
Synonyms	2-(4-Fluorophenylamino)-4-chloro-5,6-dimethylpyrimidine; 4-Chloro-5,6-dimethyl-N-(4-fluorophenyl)pyrimidin-2-amine; 4-Chloro-5,6-dimethyl-2-(p-fluoroanilino)pyrimidine; 199463-20-2; 4-Fluorophenylamino pyrimidine derivative; 2-Amino-4-chloro-5,6-dimethylpyrimidine, N-(4-fluorophenyl)-; 4-Chloro-5,6-dimethyl-2-[(4-fluorophenyl)amino]pyrimidine
EINECS	Contact for details

Quality Control

Our 4-Chloro-5,6-Dimethyl-2-(4-Fluorophenylamino)Pyrimidine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.