Description

2-[(4-Fluoro-Phenylamino)-Methyl]-Phenol is a specialized organic intermediate featuring a phenolic core linked to a fluorinated aniline moiety. This unique bifunctional structure makes it a valuable building block for synthesizing more complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the fine chemical and pharmaceutical industries for creating novel active compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders or possessing antimicrobial properties.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, or insecticides, leveraging the fluorine atom for enhanced bioactivity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating novel chelating ligands or organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of specialty polymers, dyes, or advanced organic materials where the phenol and aniline functionalities are critical.
• Academic & Industrial R&D: A versatile scaffold for medicinal chemistry programs and exploratory synthetic chemistry in both university and corporate laboratory settings.

Basic Information

Product Name	2-[(4-Fluoro-Phenylamino)-Methyl]-Phenol
CAS No.	198879-38-8
Molecular Formula	C13H12FNO
Molecular Weight	217.24 g/mol
Synonyms	2-[(4-Fluoroanilino)methyl]phenol; Phenol, 2-[(4-fluorophenylamino)methyl]-; N-(4-Fluorophenyl)-2-hydroxybenzylamine; 2-[(4-Fluorophenylamino)methyl]phenol; (2-Hydroxybenzyl)(4-fluorophenyl)amine; 4-Fluoro-N-(2-hydroxybenzyl)aniline
EINECS	Contact for details

Quality Control

Every batch of 2-[(4-Fluoro-Phenylamino)-Methyl]-Phenol is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.