Description

Fmoc-D-Orn(Mtt)-Oh is a protected amino acid derivative specifically engineered for solid-phase peptide synthesis (SPPS). This compound is a critical building block for the controlled assembly of complex peptides and peptidomimetics, offering orthogonal protection strategies essential for advanced research. It is primarily utilized by pharmaceutical R&D teams, biotechnology companies, and academic laboratories focused on developing novel therapeutic peptides, diagnostic agents, and biochemical probes.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the sequential coupling of amino acids, particularly where side-chain protection with the Mtt (4-methyltrityl) group is required.
• Orthogonal Peptide Synthesis: Enables complex peptide assembly through selective deprotection strategies, allowing for the synthesis of peptides with challenging sequences or modifications.
• Pharmaceutical Research: Used in the discovery and development of peptide-based drugs, including hormone analogs, antimicrobial peptides, and targeted therapeutics.
• Bioconjugation and Probe Development: Serves as a precursor for creating labeled peptides or peptide conjugates used in imaging, diagnostics, and targeted drug delivery systems.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening to identify bioactive peptide leads.
• Academic and Industrial R&D: A fundamental reagent for studies in biochemistry, medicinal chemistry, and chemical biology exploring protein-protein interactions and structure-activity relationships.

Basic Information

Product Name	Fmoc-D-Orn(Mtt)-Oh
CAS No.	198545-20-9
Molecular Formula	C41H38N2O5
Molecular Weight	638.75 g/mol
Synonyms	Fmoc-D-ornithine(Mtt)-OH; N-α-Fmoc-N-δ-(4-methyltrityl)-D-ornithine; Fmoc-D-Orn(4-Mtt)-OH; (2R)-5-[[(4-Methylphenyl)diphenylmethyl]amino]-2-(9H-fluoren-9-ylmethoxycarbonylamino)pentanoic acid; N-δ-(4-Methyltrityl)-N-α-(9-fluorenylmethoxycarbonyl)-D-ornithine; Fmoc-D-Orn(Mtt)-OH CAS 198545-20-9; D-Orn(Mtt)-OH Fmoc derivative
EINECS	Contact for details

Quality Control

Every batch of Fmoc-D-Orn(Mtt)-Oh is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistency, meeting the exacting standards required for advanced peptide synthesis. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.