Description

Fmoc-Asparaginol(Trt) CAS NO 198543-08-7 is a protected asparagine derivative, specifically designed for use in solid-phase peptide synthesis (SPPS). This compound is critical for the efficient and high-fidelity incorporation of asparagine into complex peptide chains, preventing unwanted side reactions. It is an essential building block for pharmaceutical R&D, biotechnology, and academic research focused on developing novel peptide-based therapeutics, diagnostics, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid derivative for the automated synthesis of complex peptides and small proteins.
• Pharmaceutical Research: Used in the discovery and development of peptide-based drugs, including hormones, enzyme inhibitors, and targeted therapies.
• Bioconjugation: Serves as a precursor for creating peptide conjugates with other molecules like dyes, polymers, or drug payloads.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening to identify bioactive peptide leads.
• Academic & Biochemical Research: Fundamental reagent for studying protein structure-function relationships, enzyme-substrate interactions, and signal transduction pathways.
• Production of Custom Peptides: Used by CROs and CDMOs for the reliable and scalable manufacture of therapeutic and research-grade peptides.

Basic Information

Product Name	Fmoc-Asparaginol(Trt)
CAS No.	198543-08-7
Molecular Formula	C39H34N2O5
Molecular Weight	610.70 g/mol
Synonyms	Fmoc-Asn(Trt)-OH; Fmoc-Nδ-trityl-L-asparagine; Nα-(9-Fluorenylmethoxycarbonyl)-Nδ-trityl-L-asparagine; (2S)-5-Oxo-2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-5-(tritylamino)pentanoic acid; Fmoc-L-Asn(Trt)-OH; N-α-Fmoc-N-δ-trityl-L-asparagine; Fmoc-Asn(Trt)
EINECS	Contact for details

Quality Control

Our Fmoc-Asparaginol(Trt) is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation by NMR and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥98.0%
Specific Rotation	-15.0° to -18.0° (c=1, DMF)
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.