Description

Boc-D-Cys(Bzl)-Ol CAS NO 198470-16-5 is a protected D-cysteine derivative, specifically a Boc-protected amino alcohol, serving as a crucial chiral building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring high-purity, stereochemically defined intermediates for the construction of complex peptides and peptidomimetics. It is primarily utilized by the pharmaceutical, biotechnology, and fine chemical industries for applications in drug discovery, API development, and the synthesis of specialized bioactive molecules.

Application

• Pharmaceutical Intermediate: Key chiral synthon in the research and development of novel therapeutic peptides and protease inhibitors.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate D-cysteine residues with orthogonal side-chain protection (Bzl) and N-terminal protection (Boc).
• Chemical Biology Probes: Building block for creating labeled or modified peptides used in biochemical assays and target identification studies.
• API Development: Intermediate in the synthetic route of active pharmaceutical ingredients (APIs) that contain non-natural or D-amino acids to enhance metabolic stability.
• Ligand and Catalyst Preparation: Precursor for synthesizing chiral ligands or organocatalysts used in asymmetric synthesis.
• Academic & Industrial Research: Fundamental reagent for methodological development in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	Boc-D-Cys(Bzl)-Ol
CAS No.	198470-16-5
Molecular Formula	C15H21NO3S
Molecular Weight	295.40 g/mol
Synonyms	(R)-2-((tert-Butoxycarbonyl)amino)-3-(benzylthio)propan-1-ol; N-(tert-Butoxycarbonyl)-D-cysteine benzyl ester alcohol; Boc-D-cysteine(Bzl)-ol; Boc-D-Cys(Bzl)-OH reduced; tert-Butyl ((R)-1-(hydroxymethyl)-2-(benzylthio)ethyl)carbamate; D-Cysteine, N-[(1,1-dimethylethoxy)carbonyl]-, benzyl ester, alcohol; Boc-D-Cys(Bzl) alcohol
EINECS	Contact for details

Quality Control

Our Boc-D-Cys(Bzl)-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% D-isomer
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Single Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.