Description

Pyrimidine, 5-Methyl-2-(Trifluoromethyl)- (9Ci) is a specialized fluorinated pyrimidine derivative, a high-value building block in advanced organic synthesis. Its core value lies in the unique combination of the pyrimidine heterocycle and the trifluoromethyl group, which is critical for modulating the physicochemical and biological properties of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to develop novel active ingredients with enhanced metabolic stability, bioavailability, and lipophilicity.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel small-molecule drugs, particularly in oncology, antiviral, and central nervous system (CNS) therapeutic areas.
• Agrochemical Active Ingredient Precursor: Used in the synthesis of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group improves efficacy and environmental profile.
• Material Science Research: Serves as a monomer or functional additive in the development of specialty polymers, liquid crystals, and electronic materials.
• Chemical Biology & Proteomics: Employed as a tagged molecular probe or a core scaffold in fragment-based drug discovery (FBDD) and bio-conjugation chemistry.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring the introduction of a fluorinated pyrimidine moiety.

Basic Information

Product Name	Pyrimidine, 5-Methyl-2-(Trifluoromethyl)- (9Ci)
CAS No.	198404-31-8
Molecular Formula	C6H5F3N2
Molecular Weight	162.11 g/mol
Synonyms	5-Methyl-2-(trifluoromethyl)pyrimidine; 2-Trifluoromethyl-5-methylpyrimidine; 5-Methyl-2-trifluoromethylpyrimidine; 2-(Trifluoromethyl)-5-methylpyrimidine; 5-Methyl-2-(trifluoromethyl)pyrimidine (9CI); 198404-31-8; 5-Methyl-2-(trifluoromethyl)pyrimidine (9CI)
EINECS	Contact for details

Quality Control

Our production of Pyrimidine, 5-Methyl-2-(Trifluoromethyl)- (9Ci) adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure consistency and reliability for sensitive synthetic applications. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.