Description

Tyr-Amyloid P Component (27-38) Amide is a synthetic peptide fragment corresponding to a specific sequence of the human Amyloid P component protein. This high-purity peptide is a critical research tool for studying protein aggregation mechanisms and the role of Amyloid P in systemic amyloidosis and other inflammatory diseases. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and diagnostic developers focused on advancing therapeutic and diagnostic strategies for amyloid-related disorders.

Application

• Biomedical Research: Used as a reference standard and antigen in studies investigating the structure, function, and aggregation kinetics of serum amyloid P component.
• Drug Discovery: Serves as a key reagent in high-throughput screening assays to identify and validate novel inhibitors of amyloid fibril formation.
• Antibody Production: Acts as an immunogen for generating specific polyclonal or monoclonal antibodies for diagnostic and research applications.
• Diagnostic Development: Employed in the development and calibration of immunoassays (e.g., ELISA) to detect amyloid-related biomarkers in biological samples.
• Biophysical Studies: Utilized in techniques such as circular dichroism (CD) spectroscopy and surface plasmon resonance (SPR) to analyze protein-protein interactions and conformational changes.

Basic Information

Product Name	Tyr-Amyloid P Component (27-38) Amide
CAS No.	198268-71-2
Molecular Formula	C71H108N20O21S
Molecular Weight	1601.8 g/mol
Synonyms	Tyr-Amyloid P (27-38) Amide; Amyloid P Component (27-38) (Tyr) Amide; APCS (27-38) (Tyr) Amide; Serum Amyloid P Component Peptide (27-38) (Tyr) Amide; Y27-Amyloid P (27-38)-NH2; H-Tyr-Gln-Leu-Ser-Gly-Trp-Pro-Phe-Leu-His-Val-NH2; YQLSGWPFLHV-NH2
EINECS	Contact for details

Quality Control

Every batch of Tyr-Amyloid P Component (27-38) Amide is manufactured and analyzed under strict quality management systems. Our products undergo rigorous purity verification using advanced analytical techniques including HPLC and mass spectrometry to ensure compliance with research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and peptide content is provided with each shipment to guarantee traceability and reliability for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to store desiccated. Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 70%
Amino Acid Analysis	Within ± 10% of theoretical
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 8.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.