Description

2'-Trifluoromethyl-Biphenyl-4-Carbaldehyde is a high-purity aromatic aldehyde building block featuring a strategically positioned trifluoromethyl group. This compound is valued for its role as a critical intermediate in advanced organic synthesis, where its unique electronic and steric properties enable the construction of complex molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting inflammation, oncology, and central nervous system disorders.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the creation of novel organic electronic materials, liquid crystals, and polymers due to its aromatic and fluorinated characteristics.
• Custom Synthesis & Contract Manufacturing: An essential building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	2'-Trifluoromethyl-Biphenyl-4-Carbaldehyde
CAS No.	198205-95-7
Molecular Formula	C14H9F3O
Molecular Weight	250.22 g/mol
Synonyms	[4-(2-Trifluoromethylphenyl)phenyl]methanal; 4'-(Trifluoromethyl)[1,1'-biphenyl]-4-carboxaldehyde; 2-(Trifluoromethyl)biphenyl-4-carbaldehyde; 4-Formyl-2'-(trifluoromethyl)biphenyl; Biphenyl-4-carbaldehyde, 2'-(trifluoromethyl)-; 2'-Trifluoromethyl-4-biphenylcarboxaldehyde
EINECS	Contact for details

Quality Control

Our 2'-Trifluoromethyl-Biphenyl-4-Carbaldehyde is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, confirming compliance with client specifications and internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.