Description

(2'-Trifluoromethylbiphenyl-4-Yl)-Methanol is a high-value fluorinated biphenyl derivative, serving as a critical building block in advanced organic synthesis. Its core value proposition lies in the trifluoromethyl group, which imparts unique electronic and metabolic properties to target molecules, enhancing their potency and stability. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and fine-tuning molecular properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in areas like oncology, CNS disorders, and inflammation.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the CF3 group improves lipophilicity and biological activity.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals for high-performance displays.
• Organic Light-Emitting Diodes (OLEDs): Employed in the development of electron-transport or host materials for OLED devices.
• Advanced Material Science: Acts as a monomer or modifier in the creation of specialty polymers with enhanced chemical resistance and thermal stability.
• Chemical Research & Development: A versatile reagent for medicinal chemistry, process chemistry, and exploring new synthetic methodologies involving fluorinated aromatics.

Basic Information

Item	Details
Product Name	(2'-Trifluoromethylbiphenyl-4-Yl)-Methanol
CAS No.	198205-80-0
Molecular Formula	C14H11F3O
Molecular Weight	252.23 g/mol
Synonyms	[4-(2-Trifluoromethylphenyl)phenyl]methanol; (2'-Trifluoromethyl[1,1'-biphenyl]-4-yl)methanol; α-(2'-Trifluoromethylbiphenyl-4-yl)methanol; 2'-Trifluoromethylbiphenyl-4-carbinol; 4-(Hydroxymethyl)-2'-(trifluoromethyl)biphenyl; (2'-Trifluoromethyl-4-biphenylyl)methanol; Biphenyl-4-ylmethanol, 2'-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our (2'-Trifluoromethylbiphenyl-4-Yl)-Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for use as a pharmaceutical intermediate.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.