Description

4-Pyrimidinamine, 5-Chloro-2-Fluoro- (9Ci) is a high-purity halogenated pyrimidine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure makes it an invaluable intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for creating complex, high-value molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of potential drug candidates, particularly in antiviral, anticancer, and kinase inhibitor research.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and pesticides, leveraging its halogenated pyrimidine core.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry and structure-activity relationship (SAR) studies.
• Material Science Precursor: Potential use in the synthesis of organic electronic materials and ligands for catalysis.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and proprietary intermediates.

Basic Information

Product Name	4-Pyrimidinamine, 5-Chloro-2-Fluoro- (9Ci)
CAS No.	196600-97-2
Molecular Formula	C4H3ClFN3
Molecular Weight	147.54 g/mol
Synonyms	5-Chloro-2-fluoropyrimidin-4-amine; 5-Chloro-2-fluoro-4-pyrimidinamine; 2-Fluoro-5-chloropyrimidin-4-amine; 4-Amino-5-chloro-2-fluoropyrimidine; 5-Chloro-2-fluoro-4-aminopyrimidine; 2-Fluoro-5-chloro-4-pyrimidinamine; 196600-97-2; FCAP
EINECS	Contact for details

Quality Control

Every batch of 5-Chloro-2-fluoropyrimidin-4-amine is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure traceability and compliance with your project requirements. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.