Description

1(2H)-Phthalazinone, 5(Or 8)-Amino-4-(2,3,5-Tri-o-Benzoyl-.Beta.-D-Ribofuranosyl)Oxy- is a sophisticated nucleoside derivative and a key protected intermediate in synthetic organic chemistry. This compound is critical for the development of novel pharmaceuticals and nucleoside analogs, offering a protected ribofuranosyl scaffold for precise chemical manipulation. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of antiviral agents, anticancer drugs, and other biologically active nucleosides.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel nucleoside-based antiviral and anticancer therapeutics.
• Antiviral Drug Research: Used in the development of prodrugs and active pharmaceutical ingredients (APIs) targeting viral polymerases.
• Oncology Research: Serves as a precursor in the creation of nucleoside analogs designed to inhibit cancer cell proliferation.
• Biochemical Tool Development: Employed in the synthesis of labeled compounds or probes for studying enzymatic mechanisms and metabolic pathways.
• Process Chemistry & Scale-up: Used in route development and optimization for the commercial-scale production of specialty nucleosides.
• Academic & Contract Research: A valuable reagent for universities and CROs conducting fundamental research in medicinal and synthetic chemistry.

Basic Information

Item	Details
Product Name	1(2H)-Phthalazinone, 5(Or 8)-Amino-4-(2,3,5-Tri-o-Benzoyl-.Beta.-D-Ribofuranosyl)Oxy-
CAS No.	195455-94-8
Molecular Formula	C34H27N3O8
Molecular Weight	605.60 g/mol
Synonyms	5(8)-Amino-4-[(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)oxy]phthalazin-1(2H)-one; 4-[(2,3,5-Tri-O-benzoyl-β-D-ribofuranosyl)oxy]-5(8)-amino-1(2H)-phthalazinone; 5-Amino-4-((2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)oxy)phthalazin-1(2H)-one; 8-Amino-4-((2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)oxy)phthalazin-1(2H)-one; Tri-O-benzoyl protected amino-phthalazinone nucleoside; Benzoylated ribofuranosyl phthalazinone derivative
EINECS	Contact for details

Quality Control

Our 1(2H)-Phthalazinone, 5(Or 8)-Amino-4-(2,3,5-Tri-o-Benzoyl-.Beta.-D-Ribofuranosyl)Oxy- is produced under strict quality management systems. Each batch undergoes comprehensive analytical characterization including HPLC for purity, NMR for structural confirmation, and mass spectrometry to ensure identity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.