Description

Fmoc-3,5-Dinitro-Tyr-Oh is a protected, non-natural tyrosine derivative specifically engineered for advanced peptide synthesis. This compound is critical for researchers and manufacturers requiring the precise incorporation of a modified aromatic amino acid with unique electronic and steric properties into peptide chains. It is primarily utilized in pharmaceutical R&D for the development of novel peptide-based therapeutics, diagnostic probes, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key building block (Fmoc-amino acid) for the controlled assembly of complex peptides, particularly where a modified tyrosine residue is required.
• Pharmaceutical Research: Synthesis of peptide drug candidates, enzyme inhibitors, and receptor ligands that exploit the distinctive properties of the 3,5-dinitrotyrosine moiety.
• Proteomics & Biochemical Studies: Creation of custom peptides used as substrates, inhibitors, or probes in enzymatic assays and protein interaction studies.
• Material Science: Potential use in synthesizing specialty peptides for surface functionalization or creating novel biomaterials with specific electronic characteristics.
• Academic Research: A valuable reagent for university and institutional labs exploring peptide chemistry, post-translational modifications, and structure-activity relationships.

Basic Information

Item	Details
Product Name	Fmoc-3,5-Dinitro-Tyr-Oh
CAS No.	195434-42-5
Molecular Formula	C24H19N3O8
Molecular Weight	477.43 g/mol
Synonyms	Fmoc-3,5-dinitro-L-tyrosine; N-(9-Fluorenylmethoxycarbonyl)-3,5-dinitro-L-tyrosine; (2S)-2-[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]-3-(3,5-dinitro-4-hydroxyphenyl)propanoic acid; Fmoc-Tyr(3,5-NO2)-OH; Fmoc-Dinitrotyrosine-OH; Nα-Fmoc-Nω-3,5-dinitro-L-tyrosine
EINECS	Contact for details

Quality Control

Every batch of Fmoc-3,5-Dinitro-Tyr-Oh is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure high purity and batch-to-batch consistency, which is critical for reproducible results in sensitive peptide synthesis applications. A detailed Certificate of Analysis (COA) providing purity, identity, and impurity profiles is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.