Description

4-(9H-Fluoren-9-Ylmethoxycarbonylamino)-1-Methyl-1H-Pyrrole-2-Carboxylic Acid is a specialized Fmoc-protected amino acid derivative, a critical building block in modern solid-phase peptide synthesis (SPPS). Its primary value lies in enabling the controlled and efficient construction of complex peptide sequences, particularly those incorporating modified pyrrole-based amino acids. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors developing novel peptide-based therapeutics, diagnostics, and research tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key Fmoc-protected amino acid building block for the automated synthesis of custom peptides.
• Pharmaceutical Research: Synthesis of peptide drug candidates, including potential oncology, metabolic, and neurological disorder treatments.
• Bioconjugation: Used to introduce specific functional handles or modified amino acid structures into peptides for labeling or conjugation with other biomolecules.
• Chemical Biology Probes: Construction of specialized peptides used as probes to study protein-protein interactions and enzyme function.
• Peptide Library Production: A component in combinatorial chemistry for generating diverse peptide libraries for high-throughput screening.
• API Intermediate: Serves as a critical raw material in the multi-step synthesis of Active Pharmaceutical Ingredients (APIs) for peptide drugs.

Basic Information

Product Name	4-(9H-Fluoren-9-Ylmethoxycarbonylamino)-1-Methyl-1H-Pyrrole-2-Carboxylic Acid
CAS No.	195387-29-2
Molecular Formula	C21H18N2O4
Molecular Weight	362.38 g/mol
Synonyms	Fmoc-4-Amino-1-methyl-1H-pyrrole-2-carboxylic acid; 1-Methyl-4-[(9H-fluoren-9-ylmethoxy)carbonylamino]-1H-pyrrole-2-carboxylic acid; 4-(Fmoc-amino)-1-methyl-1H-pyrrole-2-carboxylic acid; Fmoc-MePyr(4-NH2)-OH; N-α-Fmoc-4-amino-1-methylpyrrole-2-carboxylic acid; N4-(9-Fluorenylmethoxycarbonyl)-1-methyl-4-amino-2-pyrrolecarboxylic acid
EINECS	Contact for details

Quality Control

Our 4-(9H-Fluoren-9-Ylmethoxycarbonylamino)-1-Methyl-1H-Pyrrole-2-Carboxylic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for sensitive research and GMP applications. All products undergo rigorous analytical testing, including HPLC for purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.