Description

2,4-Dimethoxy-3,5-Difluorobenzenamine is a high-purity, multi-functional aromatic amine building block featuring strategically placed fluorine and methoxy substituents. This compound is critical for the synthesis of complex molecules, offering unique electronic and steric properties that influence reactivity and biological activity. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the difluoro-dimethoxy motif can enhance bioavailability and environmental stability.
• Ligand & Catalyst Development: Serves as a sophisticated building block for creating novel ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the synthesis of specialty polymers, liquid crystals, and organic electronic materials due to its electron-donating methoxy groups and fluorine atoms.
• Chemical Biology Probes: Acts as a versatile scaffold for developing fluorescent tags, molecular probes, and other tools for biochemical research and diagnostics.

Basic Information

Product Name	2,4-Dimethoxy-3,5-Difluorobenzenamine
CAS No.	195136-67-5
Molecular Formula	C8H9F2NO2
Molecular Weight	189.16 g/mol
Synonyms	3,5-Difluoro-2,4-dimethoxyaniline; 2,4-Dimethoxy-3,5-difluoroaniline; 3,5-Difluoro-2,4-dimethoxybenzenamine; Benzenamine, 3,5-difluoro-2,4-dimethoxy-; 2,4-Dimethoxy-3,5-difluorophenylamine; 3,5-Difluoro-2,4-dimethoxyphenylamine
EINECS	Contact for details

Quality Control

Our 2,4-Dimethoxy-3,5-Difluorobenzenamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring cGMP and ISO 9001 standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.