Description

7-Bromo-1H-Quinazolin-4-One is a versatile brominated quinazolinone derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a functionalized core structure for constructing complex molecules with targeted biological activity. This high-purity intermediate is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing novel therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other small-molecule drug candidates targeting various disease pathways.
• Agrochemical Research: Used in developing novel active ingredients for crop protection products, leveraging its heterocyclic scaffold.
• Chemical Biology & Proteomics: Serves as a core scaffold for designing chemical probes and tool compounds to study enzyme function and protein interactions.
• Material Science: Potential building block for creating organic electronic materials or metal-organic frameworks (MOFs) due to its aromatic structure and bromine handle.
• Academic & Contract Research: Essential for medicinal chemistry programs in universities and CROs (Contract Research Organizations) exploring new chemical entities.

Basic Information

Product Name	7-Bromo-1H-Quinazolin-4-One
CAS No.	194851-16-6
Molecular Formula	C8H5BrN2O
Molecular Weight	225.04 g/mol
Synonyms	7-Bromoquinazolin-4(1H)-one; 7-Bromo-4-hydroxyquinazoline; 4-Hydroxy-7-bromoquinazoline; 7-Bromo-1,4-dihydroquinazolin-4-one; 194851-16-6; 7-Bromo-4(1H)-quinazolinone; 7-Brom-1H-chinazolin-4-on (German); 7-ブロモ-1H-キナゾリン-4-オン (Japanese)
EINECS	Contact for details

Quality Control

Our 7-Bromo-1H-Quinazolin-4-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep the container sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.