Description

Cyclobutanecarboxylic Acid, 3-[4-Amino-5-[3-(Phenylmethoxy)Phenyl]-7H-Pyrrolo[2,3-D]Pyrimidin-7-Yl]-, Ethyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant commercial importance for its role in the synthesis of targeted therapeutic agents, particularly kinase inhibitors. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of novel small-molecule drugs for oncology and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of proprietary kinase inhibitor candidates for cancer therapy.
• Biochemical Research: Used as a reference standard or a key precursor in medicinal chemistry programs for structure-activity relationship (SAR) studies.
• Preclinical Development: Serves as a starting material for producing active pharmaceutical ingredients (APIs) during early-stage drug development and scale-up processes.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the cGMP production of investigational new drugs.

Basic Information

Product Name	Cyclobutanecarboxylic Acid, 3-[4-Amino-5-[3-(Phenylmethoxy)Phenyl]-7H-Pyrrolo[2,3-D]Pyrimidin-7-Yl]-, Ethyl Ester
CAS No.	194788-04-0
Molecular Formula	C26H26N4O3
Molecular Weight	442.51 g/mol
Synonyms	Ethyl 3-[4-Amino-5-[3-(benzyloxy)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-7-yl]cyclobutanecarboxylate; 194788-04-0; 3-[4-Amino-5-[3-(phenylmethoxy)phenyl]pyrrolo[2,3-d]pyrimidin-7-yl]cyclobutanecarboxylic acid ethyl ester; UNII-9G3H1J4F6S; 9G3H1J4F6S; CS-0536665; AK-968/31533053; A937099; Ethyl 3-(4-amino-5-(3-(benzyloxy)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)cyclobutanecarboxylate
EINECS	Contact for details

Quality Control

Our Cyclobutanecarboxylic Acid, 3-[4-Amino-5-[3-(Phenylmethoxy)Phenyl]-7H-Pyrrolo[2,3-D]Pyrimidin-7-Yl]-, Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent specifications required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.