Description

5-(3-(Benzyloxy)Phenyl)-3H-Pyrrolo[2,3-D]Pyrimidin-4-Amine is a high-purity, advanced pharmaceutical intermediate belonging to the pyrrolopyrimidine class of heterocyclic compounds. This compound matters as a critical building block in medicinal chemistry, enabling the synthesis of targeted therapeutic agents. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of kinase inhibitors and other small-molecule drugs for oncology and inflammatory diseases.

Application

This specialized intermediate serves as a key precursor in several high-value research and development applications:

• Pharmaceutical Intermediate: Core scaffold for the synthesis of novel kinase inhibitors targeting various cancer pathways.
• Medicinal Chemistry Research: A versatile building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: Used in vitro to study enzyme inhibition mechanisms and cellular signaling pathways.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in API manufacturing.
• Preclinical Development: Employed in the synthesis of candidate drugs for pharmacological and toxicological evaluation.

Basic Information

Product Name	5-(3-(Benzyloxy)Phenyl)-3H-Pyrrolo[2,3-D]Pyrimidin-4-Amine
CAS No.	194787-36-5
Molecular Formula	C19H16N4O
Molecular Weight	316.36 g/mol
Synonyms	5-[3-(Benzyloxy)phenyl]-3H-pyrrolo[2,3-d]pyrimidin-4-amine; 4-Amino-5-(3-benzyloxyphenyl)-3H-pyrrolo[2,3-d]pyrimidine; 194787-36-5; 5-(3-Benzyloxyphenyl)-3H-pyrrolo[2,3-d]pyrimidin-4-amine; Pyrrolo[2,3-d]pyrimidin-4-amine, 5-[3-(phenylmethoxy)phenyl]-; BBT-594; BBT 594
EINECS	Contact for details

Quality Control

Our 5-(3-(Benzyloxy)Phenyl)-3H-Pyrrolo[2,3-D]Pyrimidin-4-Amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, supporting compliance in regulated R&D and cGMP environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.