Description

Cyclopentaneacetic Acid, 3-Amino-3-Carboxy-, trans- (9Ci) is a high-purity, non-proteinogenic amino acid derivative featuring a unique cyclopentane backbone. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, enabling the construction of complex molecular architectures with precise stereochemistry. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), peptide mimetics, and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, including protease inhibitors and receptor modulators.
• Peptidomimetics Research: Used to incorporate constrained, non-natural amino acid motifs into peptide backbones to enhance metabolic stability and bioavailability.
• Asymmetric Synthesis: Serves as a valuable starting material or auxiliary in catalytic asymmetric reactions to introduce stereogenic centers.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds or molecular probes for studying enzyme mechanisms and biological pathways.
• Fine Chemical Production: An intermediate in the multi-step synthesis of complex, high-value specialty chemicals for various industrial applications.
• Academic & Contract Research: Essential for methodological development in organic chemistry and for custom synthesis projects in CRO/CMO settings.

Basic Information

Product Name	Cyclopentaneacetic Acid, 3-Amino-3-Carboxy-, trans- (9Ci)
CAS No.	194785-81-4
Molecular Formula	C8H13NO4
Molecular Weight	187.19 g/mol
Synonyms	(1R,3S)-3-Aminocyclopentane-1-carboxylic acid; trans-3-Aminocyclopentane-1-carboxylic acid; (1R,3S)-3-Amino-1-cyclopentanecarboxylic acid; 3-Amino-1-cyclopentanecarboxylic acid, trans-; 3-ACPC; trans-3-ACPC; (1R,3S)-ACPC; NSC 339524
EINECS	Contact for details

Quality Control

Our Cyclopentaneacetic Acid, 3-Amino-3-Carboxy-, trans- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and fine chemical synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and specific impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% de (trans isomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.