Description

Pz-Pro-Oh CAS NO 194541-47-4 is a specialized chemical building block, specifically a protected amino acid derivative. This compound is of significant value in advanced organic synthesis, particularly in peptide chemistry, where it serves as a key intermediate for constructing complex molecular architectures. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel therapeutic agents and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Critical for the synthesis of peptide-based active pharmaceutical ingredients (APIs) and prodrugs.
• Peptide Synthesis: Used as a protected amino acid derivative in solid-phase and solution-phase peptide synthesis (SPPS).
• Bioconjugation: Serves as a linker or spacer molecule in the development of antibody-drug conjugates (ADCs) and other bioconjugates.
• Proteomics Research: Employed in biochemical research for studying enzyme mechanisms and protein-protein interactions.
• Combinatorial Chemistry: A valuable building block for creating diverse chemical libraries in drug discovery platforms.
• Fine Chemical Production: Utilized in the custom synthesis of complex organic molecules for agrochemical and material science applications.

Basic Information

Product Name	Pz-Pro-Oh
CAS No.	194541-47-4
Molecular Formula	C11H18N2O3
Molecular Weight	226.27 g/mol
Synonyms	1-(Phenylazocarbonyl)-L-proline; L-Proline, 1-[(phenylamino)carbonyl]-; 1-[(Phenylcarbamoyl)]proline; 1-Carbamoyl-L-proline, N-phenyl-; Pz-Pro-OH; Fmoc-Pro-OH (Note: Common related derivative); (S)-1-(Phenylcarbamoyl)pyrrolidine-2-carboxylic acid; N-Carboxyproline anilide
EINECS	Contact for details

Quality Control

Our Pz-Pro-Oh is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the high standards required for research and cGMP manufacturing. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.