Description

n-Me-Val-Leu-Anilide CAS NO 194351-54-7 is a specialized synthetic peptide derivative, primarily utilized as a key intermediate in advanced pharmaceutical research and development. Its value lies in enabling the synthesis of complex peptide-based compounds, which are critical for drug discovery programs targeting various therapeutic areas. This high-purity intermediate is essential for research laboratories and pharmaceutical manufacturers focused on developing novel active pharmaceutical ingredients (APIs) and peptidomimetics.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel peptide-based drugs and therapeutic agents.
• Protease Inhibitor Research: Used in the development and study of enzyme inhibitors, particularly for proteases like dipeptidyl peptidase IV (DPP-IV).
• Peptidomimetic Synthesis: Serves as a core structure for creating peptidomimetics, which mimic the function of natural peptides with enhanced stability and bioavailability.
• Biochemical Tool Compound: Employed in academic and industrial research as a standard or reference compound in metabolic and enzymatic studies.
• API Development: Integral to the R&D pipeline for Active Pharmaceutical Ingredients targeting metabolic disorders and other conditions.
• Custom Peptide Synthesis: Used by contract research and manufacturing organizations (CRMOs) for producing custom peptide sequences for clients.

Basic Information

Product Name	n-Me-Val-Leu-Anilide
CAS No.	194351-54-7
Molecular Formula	C19H31N3O2
Molecular Weight	333.47 g/mol
Synonyms	N-Methyl-L-valyl-N-[(1S)-1-(phenylamino)carbonyl-3-methylbutyl]-L-leucinamide; N-Methylvalyl-leucyl-anilide; (S)-N-(1-((S)-1-((Methylamino)-3-methyl-1-oxobutan-2-yl)amino)-3-methyl-1-oxopentan-2-yl)benzamide; Valine, N-methyl-, 1-[(1S)-1-[[(phenylamino)carbonyl]amino]-3-methylbutyl]leucinamide; DPP-IV Inhibitor Intermediate; Peptide Anilide Derivative
EINECS	Contact for details

Quality Control

Our n-Me-Val-Leu-Anilide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and chiral purity analysis to ensure it meets the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and purity. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.2%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.