Description

Hexadecanoic Acid, 2-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-, (S)- is a high-purity, chiral amino acid derivative specifically designed for advanced chemical synthesis. This compound is a critical building block in the production of complex peptides and other biologically active molecules, offering precise stereochemical control. It is primarily utilized by pharmaceutical research organizations, biotechnology companies, and fine chemical manufacturers engaged in the development of novel therapeutics and high-value specialty chemicals.

Application

• Solid-Phase Peptide Synthesis (SPPS): As an Fmoc-protected amino acid derivative, it serves as a key monomer for the controlled assembly of peptide chains.
• Pharmaceutical Intermediates: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring specific chiral centers.
• Bioconjugation: Used to modify proteins, antibodies, or other biomolecules by introducing a palmitic acid (hexadecanoic acid) moiety, often for lipidation studies or to alter pharmacokinetic properties.
• Research & Development: Employed in academic and industrial R&D for exploring new synthetic methodologies and creating custom peptide libraries for screening.
• Production of Lipopeptides: Integral for synthesizing lipopeptides, which have applications as antimicrobial agents, vaccines, and drug delivery systems.

Basic Information

Product Name	Hexadecanoic Acid, 2-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-, (S)-
CAS No.	193885-60-8
Molecular Formula	C31H41NO5
Molecular Weight	507.66 g/mol
Synonyms	Fmoc-L-homoalanine-OH; Fmoc-D-homoalanine-OH (enantiomer); N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-homoalanine; 2-[(Fmoc-amino)]hexadecanoic acid; Fmoc-HomoAla-OH; Nα-Fmoc-L-2-aminopalmitic acid; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)hexadecanoic acid; Fmoc-2-Aminohexadecanoic Acid
EINECS	Contact for details

Quality Control

Our Hexadecanoic Acid, 2-[[(9H-Fluoren-9-Ylmethoxy)Carbonyl]Amino]-, (S)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, to ensure it meets the exacting standards required for pharmaceutical and research applications. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.