Description

2-Bromo-4-Fluoro-5-(Trifluoromethyl)Aniline is a high-value halogenated aniline derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring bromo, fluoro, and trifluoromethyl substituents, makes it indispensable for introducing specific steric and electronic properties into target molecules. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic motifs for bioactivity or metabolic stability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances lipophilicity and biological activity.
• Material Science Research: Building block for creating specialized polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing substituents.
• Cross-Coupling Reactions: Serves as a substrate in Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions to construct complex biaryl systems.
• Dye and Pigment Chemistry: Intermediate for synthesizing specialized halogenated dyes and pigments with unique color fastness and spectral properties.

Basic Information

Product Name	2-Bromo-4-Fluoro-5-(Trifluoromethyl)Aniline
CAS No.	193090-60-7
Molecular Formula	C7H4BrF4N
Molecular Weight	258.01 g/mol
Synonyms	5-Amino-2-bromo-4-fluoro-α,α,α-trifluorotoluene; 2-Bromo-4-fluoro-5-(trifluoromethyl)benzenamine; 2-Bromo-α,α,α,4-tetrafluoro-m-toluidine; Benzenamine, 2-bromo-4-fluoro-5-(trifluoromethyl)-; 193090-60-7; 2-Br-4-F-5-CF3-Aniline; 2-Bromo-4-fluoro-5-trifluoromethylaniline
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Fluoro-5-(Trifluoromethyl)Aniline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and away from direct light sources to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.