Description

4-Hydrazinyl-6-(Trifluoromethyl)Pyrimidine is a high-value pyrimidine derivative, a versatile building block prized for its trifluoromethyl and hydrazinyl functional groups. Its molecular structure makes it a critical intermediate in the synthesis of advanced pharmaceuticals and agrochemicals, enabling the introduction of desirable properties like metabolic stability and lipophilicity. This compound is essential for R&D and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity.
• Material Science Research: Serves as a precursor for creating novel heterocyclic compounds and functional materials with specific electronic or optical properties.
• Chemical Biology & Proteomics: Utilized as a reactive handle in bioconjugation chemistry and for synthesizing molecular probes and inhibitors.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthetic routes and scale-up projects.

Basic Information

Product Name	4-Hydrazinyl-6-(Trifluoromethyl)Pyrimidine
CAS No.	193068-56-3
Molecular Formula	C5H5F3N4
Molecular Weight	178.12 g/mol
Synonyms	6-(Trifluoromethyl)pyrimidine-4-hydrazine; 4-Hydrazino-6-(trifluoromethyl)pyrimidine; 6-(Trifluoromethyl)-4-pyrimidinylhydrazine; 4-Pyrimidinamine, 6-(trifluoromethyl)-; 6-Trifluoromethylpyrimidine-4-ylhydrazine; 4-Hydrazinyl-6-trifluoromethyl-pyrimidine
EINECS	Contact for details

Quality Control

Our 4-Hydrazinyl-6-(Trifluoromethyl)Pyrimidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent oxidation and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.