Description

Exanta CAS NO 192939-46-1 is a high-purity, synthetic small molecule pharmaceutical intermediate. This compound is of significant commercial interest for its role in the development of novel therapeutic agents, particularly in the cardiovascular and anticoagulant research fields. It is primarily utilized by pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and fine chemical suppliers serving the global life sciences industry.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of advanced direct thrombin inhibitors and other anticoagulant APIs.
• Biochemical Research: Used as a reference standard and active probe in studies of serine protease mechanisms and coagulation pathways.
• Preclinical Development: Serves as a critical material for formulation studies, pharmacokinetic profiling, and toxicology assessments during drug candidate development.
• Process Chemistry: Employed in route scouting and optimization for the scalable production of target drug molecules.
• Custom Synthesis: Basis for the preparation of novel analogs and derivatives for structure-activity relationship (SAR) studies.

Basic Information

Item	Details
Product Name	Exanta CAS NO 192939-46-1
CAS No.	192939-46-1
Molecular Formula	C23H22N4O4
Molecular Weight	418.45 g/mol
Synonyms	Ximelagatran; H 376/95; Ethyl 2-({[(1R)-1-Cyclohexyl-2-[(2S)-2-{[(4-{[(Hexyloxy)carbonyl]amino}phenyl)methyl]carbamoyl}azetidin-1-yl]-2-oxoethyl]amino}acetate); Melagatran Prodrug; AZD-0837; Exanta (Brand Name); Direct Thrombin Inhibitor Intermediate
EINECS	Contact for details

Quality Control

Our Exanta CAS NO 192939-46-1 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent determination, to ensure it meets the stringent requirements for pharmaceutical development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a low-humidity environment to prevent moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity	≥99.0% ee
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.