Description

Adrenomedullin (26-52) (Human) is a specific bioactive peptide fragment derived from the human adrenomedullin hormone. This compound is a critical research tool for investigating cardiovascular regulation, tumor biology, and inflammatory processes. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and diagnostic developers focused on peptide-based therapeutics and biomarker discovery. CAS NO 192871-80-0.

Application

• Biomedical Research: Used as a reference standard and active agent in studies exploring the vasodilatory, angiogenic, and anti-inflammatory functions of adrenomedullin.
• Drug Discovery & Development: Serves as a key intermediate or pharmacological tool in screening assays and preclinical studies for cardiovascular and oncological drug candidates.
• Diagnostic Assay Development: Employed in the calibration and validation of immunoassays (e.g., ELISA) designed to measure adrenomedullin levels in clinical samples.
• Signal Transduction Studies: Applied in cell-based experiments to elucidate receptor binding mechanisms and downstream signaling pathways (e.g., cAMP activation).
• Academic & Institutional Research: Fundamental research into hypertension, sepsis, heart failure, and cancer where adrenomedullin pathways are implicated.
• Peptide Chemistry & Custom Synthesis: Used as a building block or template for the synthesis of novel peptide analogs with modified biological activity.

Basic Information

Product Name	Adrenomedullin (26-52) (Human)
CAS No.	192871-80-0
Molecular Formula	C136H221N41O39S
Molecular Weight	3086.6 g/mol
Synonyms	ADM (26-52), Human; Adrenomedullin Fragment 26-52; H-Arg-Tyr-Val-Gln-Trp-Ala-Val-Gly-His-Arg-Phe-NH2 (Disulfide bridge: Cys16-Cys21); AM (26-52); Preproadrenomedullin 153-179; Tryptophan-47-adrenomedullin (26-52); ADM-26; ADM (human 26-52)
EINECS	Contact for details

Quality Control

Our Adrenomedullin (26-52) (Human) is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and mass spectrometry for identity confirmation, to ensure compliance with research-grade specifications. Certificates of Analysis (COA) detailing purity, peptide content, and analytical data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Amino Acid Analysis	Within ± 10% of theoretical
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water, dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.