Description

3-Chloro-4-Fluorobenzyl Bromide is a versatile and high-purity halogenated benzyl bromide derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its reactive benzylic bromide site and the strategic substitution pattern on the aromatic ring, enabling precise molecular construction. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing substituted benzyl motifs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the chloro-fluoro substitution pattern confers specific biological activity.
• Liquid Crystal & OLED Materials: Serves as a building block for advanced electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: An effective electrophile in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) for creating complex biaryl structures.
• Functional Polymer Monomer: Incorporated into polymer chains to introduce specific halogenated aromatic functionalities, modifying material properties.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new synthetic methodologies and creating compound libraries.

Basic Information

Product Name	3-Chloro-4-Fluorobenzyl Bromide
CAS No.	192702-01-5
Molecular Formula	C7H5BrClF
Molecular Weight	223.47 g/mol
Synonyms	1-(Bromomethyl)-3-chloro-4-fluorobenzene; (3-Chloro-4-fluorophenyl)methyl bromide; α-Bromo-3-chloro-4-fluorotoluene; 3-Chloro-4-fluoro-α-bromotoluene; 3-Chloro-4-fluorobenzylbromide; 4-Fluoro-3-chlorobenzyl bromide; Benzene, 1-(bromomethyl)-3-chloro-4-fluoro-; 3-Chloro-4-fluoro benzyl bromide
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-Fluorobenzyl Bromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.