Description

Pyr-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Oh is a synthetic peptide sequence of significant interest in biochemical and pharmaceutical research. This compound, with CAS No. 192377-94-9, is valued for its specific structural and functional properties, making it a critical intermediate for advanced studies in proteomics and drug discovery. It is primarily utilized by research institutions, biotechnology companies, and pharmaceutical developers focused on peptide-based therapeutics and diagnostic tools.

Application

• Biochemical Research: Used as a reference standard or substrate in enzymatic studies and protein interaction assays.
• Pharmaceutical Development: Serves as a key intermediate or active pharmaceutical ingredient (API) in the synthesis of novel peptide-based therapeutics.
• Proteomics & Biomarker Discovery: Employed in mass spectrometry and chromatography for method development and calibration in complex biological sample analysis.
• Diagnostic Reagent Production: Acts as a critical component in the development of immunoassays and other diagnostic kits.
• Academic Research: Utilized in university and institutional labs for studying peptide structure-activity relationships and metabolic pathways.
• Cosmeceutical R&D: Investigated for potential applications in advanced skincare formulations targeting specific biological pathways.

Basic Information

Item	Details
Product Name	Pyr-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Oh
CAS No.	192377-94-9
Molecular Formula	C148H235N43O44S
Molecular Weight	3298.8 g/mol
Synonyms	Pyroglutamyl-Valyl-Histidyl-Histidyl-Glutaminyl-Lysyl-Leucyl-Valyl-Phenylalanyl-Phenylalanyl-Alanyl-Glutamyl-Aspartyl-Valyl-Glycyl-Seryl-Asparaginyl-Lysyl-Glycyl-Alanyl-Isoleucyl-Isoleucyl-Glycyl-Leucyl-Methionyl-Valyl-Glycyl-Glycyl-Valyl-Valinol; Amyloid β-Protein (1-40), Pyroglutamyl-3-; AβpE3-40; N3pE-Aβ40; Pyroglutamate-modified Aβ40; pGlu-Aβ (1-40); Aβ (pE3-40)
EINECS	Contact for details

Quality Control

Our Pyr-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Oh is manufactured under stringent quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and MS for identity confirmation, to ensure compliance with research-grade specifications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to guarantee traceability and consistency for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This hygroscopic (moisture-sensitive) material should be allowed to equilibrate to room temperature in a desiccator before opening to prevent condensation and hydrolysis. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Single Impurity (HPLC)	≤ 1.0%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.