Description

4-(4-Pyridyloxy)Benzenesulfonyl Chloride is a high-purity sulfonyl chloride derivative, a key reactive intermediate in modern synthetic chemistry. Its value lies in its ability to act as a versatile sulfonylation reagent, enabling the efficient introduction of the sulfonyl functional group into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of sulfonamide-based drug candidates, including enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides that require specific sulfonyl moiety incorporation for bioactivity.
• Material Science Research: Serves as a precursor for creating functionalized polymers, dyes, and advanced organic materials with tailored properties.
• Chemical Biology & Proteomics: Employed as a reactive probe or linker in the study of protein interactions and activity-based protein profiling (ABPP).
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research laboratories for bespoke synthesis projects requiring high-purity sulfonylation reagents.

Basic Information

Product Name	4-(4-Pyridyloxy)Benzenesulfonyl Chloride
CAS No.	192329-81-0
Molecular Formula	C11H8ClNO3S
Molecular Weight	269.70 g/mol
Synonyms	4-(Pyridin-4-yloxy)benzenesulfonyl chloride; 4-(4-Pyridinyloxy)benzenesulfonyl chloride; 1-(Pyridin-4-yloxy)-4-sulfonylchloridobenzene; p-(4-Pyridyloxy)benzenesulfonyl chloride; 4-Pyridyloxybenzenesulfonyl Chloride; Benzenesulfonyl chloride, 4-(4-pyridinyloxy)-; 192329-81-0
EINECS	Contact for details

Quality Control

Our 4-(4-Pyridyloxy)Benzenesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.