Description

L-β-Homotryptophan Hydrochloride is a high-purity, non-proteinogenic amino acid derivative, specifically the hydrochloride salt of the β-homo analog of L-tryptophan. This compound is valued for its role as a critical chiral building block and intermediate in advanced pharmaceutical synthesis and biochemical research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for applications requiring specific stereochemistry and molecular modification.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of novel therapeutic agents, including peptidomimetics and enzyme inhibitors.
• Biochemical Research: Used as a specialized substrate or analog in enzymatic studies and metabolic pathway investigations.
• Peptide Chemistry: Incorporation into custom peptide sequences to study structure-activity relationships (SAR) and enhance peptide stability.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Asymmetric Synthesis: Employed as a starting material or resolving agent in the development of asymmetric catalytic processes.
• Neuroscience Research: Potential use in studies related to neurotransmitter synthesis and modulation due to its structural similarity to tryptophan.

Basic Information

Product Name	L-β-Homotryptophan Hydrochloride
CAS No.	192003-01-3
Molecular Formula	C12H15ClN2O2
Molecular Weight	254.71 g/mol
Synonyms	(S)-2-Amino-4-(1H-indol-3-yl)butanoic acid hydrochloride; L-β-Homotryptophan HCl; H-Trp(β-homo)-OH · HCl; (S)-β-Homotryptophan hydrochloride; 3-(3-Aminopropyl)indole-2-carboxylic acid hydrochloride (tautomeric form); L-2-Amino-4-(indol-3-yl)butyric acid hydrochloride; β-Homo-L-tryptophan hydrochloride
EINECS	Contact for details

Quality Control

Our L-β-Homotryptophan Hydrochloride is manufactured under a strict quality management system. Each batch is subjected to comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets the high standards required for research and synthesis. A Certificate of Analysis (COA) detailing specific results for each batch is provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	[α]²⁰D: Specific range available on COA
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.