Description

L-β-Homothreonine HCl is a high-purity, non-proteinogenic amino acid derivative, specifically the hydrochloride salt of the L-isomer of β-homothreonine. This compound serves as a critical chiral building block and intermediate in advanced pharmaceutical synthesis and biochemical research. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require high-quality, stereochemically defined intermediates for drug discovery, peptide synthesis, and the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for complex molecules.
• Peptide Synthesis: Used as a specialized amino acid analog in the research and production of modified peptides with enhanced stability or biological activity.
• Biochemical Research: Employed as a substrate or inhibitor in enzymatic studies and metabolic pathway investigations.
• Proteomics & Cell Culture: A component in specialized media formulations for studying amino acid metabolism and protein function.
• Fine Chemical Synthesis: A versatile building block for constructing complex organic molecules in academic and industrial R&D laboratories.

Basic Information

Product Name	L-β-Homothreonine HCl
CAS No.	192003-00-2
Molecular Formula	C5H11NO3 • HCl
Molecular Weight	169.61 g/mol (Free base), 206.06 g/mol (HCl salt)
Synonyms	(2S,3S)-2-Amino-3-hydroxyhexanoic acid hydrochloride; L-β-Homothreonine hydrochloride; (2S,3S)-3-Hydroxy-2-aminohexanoic acid HCl; β-Homothreonine HCl; L-three-β-Homothreonine HCl; 3-Hydroxy-L-norleucine hydrochloride; β-Homo-L-threonine hydrochloride
EINECS	Contact for details

Quality Control

Our L-β-Homothreonine HCl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and pharmaceutical applications. A Certificate of Analysis (COA) detailing purity, identity, and specific impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent absorption of moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.