Description

[1,1-Biphenyl]-4-Acetamide, n-(4-Amino-1,2,3,6-Tetrahydro-1-Methyl-2,6-Dioxo-5-Pyrimidinyl)-4-Bromo- is a high-purity, specialized organic intermediate of significant interest in advanced chemical synthesis. Its complex molecular architecture, featuring both biphenyl and substituted pyrimidinone moieties, makes it a valuable building block for the development of novel pharmacologically active compounds. This product is primarily targeted at research institutions and pharmaceutical companies engaged in medicinal chemistry and process development for new therapeutic agents.

Application

• Pharmaceutical Intermediate: Key precursor in the research and synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology and antiviral drug discovery programs.
• Medicinal Chemistry Research: Serves as a sophisticated scaffold for structure-activity relationship (SAR) studies and lead optimization in drug development.
• Process Chemistry Development: Used in route scouting and scale-up studies for the efficient production of target drug candidates.
• Biochemical Research: Potential use as a tool compound or probe in biochemical assays to study specific enzyme or receptor interactions.
• Custom Synthesis Building Block: Employed by fine chemical manufacturers for the contract synthesis of complex, customer-specific molecules.

Basic Information

Product Name	[1,1-Biphenyl]-4-Acetamide, n-(4-Amino-1,2,3,6-Tetrahydro-1-Methyl-2,6-Dioxo-5-Pyrimidinyl)-4-Bromo-
CAS No.	191936-51-3
Molecular Formula	C19H19BrN4O3
Molecular Weight	431.29 g/mol
Synonyms	4'-Bromo-N-(4-amino-1-methyl-2,6-dioxo-1,2,3,6-tetrahydro-5-pyrimidinyl)[1,1'-biphenyl]-4-acetamide; 4-Bromo-N-(4-amino-1-methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-5-yl)biphenyl-4-acetamide; 191936-51-3; Biphenyl-4-acetamide, N-(4-amino-1,2,3,6-tetrahydro-1-methyl-2,6-dioxo-5-pyrimidinyl)-4'-bromo-; 4'-Bromo-biphenyl-4-acetic acid (4-amino-1-methyl-2,6-dioxo-1,2,3,6-tetrahydro-pyrimidin-5-yl)-amide
EINECS	Contact for details

Quality Control

Our production of [1,1-Biphenyl]-4-Acetamide, n-(4-Amino-1,2,3,6-Tetrahydro-1-Methyl-2,6-Dioxo-5-Pyrimidinyl)-4-Bromo- adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider the use of desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.